J Peripher.Nerv.Syst. Lee YS, Lorenzo BJ, Koufis T, et al. Liu J. Wang Y, Ma R. [Effect of an extract of Paeonia lactiflora on the blood coagulative and fibrinolytic enzymes]. 1999;15:499-523. J Clin Psychopharmacol 2016;36(6):572-9. J Gastroenterol 1996;31(5):691-695. Be sure to have your blood checked regularly. 2005;25(6):540-542. Hyodo T, Taira T, Kumakura M, et al. Intern Med 2017;56(2):175-9. View abstract. Das SK, Das V, Gulati AK, and et al. Effect of preoperative licorice lozenges on incidence of postextubation cough and sore throat in smokers undergoing general anesthesia and endotracheal intubation. A specific type of peony product, total glucosides of peony (TGP), has most often been used by adults in doses of 600 mg by mouth three times daily for up to 24 weeks. 2017 Sep;31(9):1330-1340. View abstract. View abstract. The herb has also been studied for use in canine atopic dermatitis along with white peony (Paeonia lactiflora) and licorice (Glycyrrhiza glabra). Licorice root and white poney is a common herbal formula for PCOS originating in traditional Chinese medicine. Cinatl J, Morgenstern B, Bauer G, et al. View abstract. View abstract. Strandberg TE, Jarvenpaa AL, Vanhanen H, McKeigue PM. Baykul, T., Alanoglu, E. G., and Kocer, G. Use of Ankaferd Blood Stopper as a hemostatic agent: a clinical experience. View abstract. J Cosmet.Sci 2006;57(1):57-64. Lethal liquorice lollies (liquorice abuse causing pseudohyperaldosteronism). 44 ($0.09/Count) NEW PACKAGING White Peony Root Bai Shao 4oz 38. . Part 2: Effect of glycyrrhizic acid on the course of illness]. Ito, M., Sato, A., Hirabayashi, K., Tanabe, F., Shigeta, S., Baba, M., De Clercq, E., Nakashima, H., and Yamamoto, N. Mechanism of inhibitory effect of glycyrrhizin on replication of human immunodeficiency virus (HIV). J Ethnopharmacol 2002;81:101-4.. View abstract. 2020;2020:8401239. View abstract. West J Med 1997;167(3):184-185. Exploring Pseudohyperaldosteronism in Glycyrrhizic Acid Toxicity From Chronic Licorice Root Consumption. Other side effects of licorice use include . Hypertension and the cortisol-cortisone shuttle. [Effect of Paeonia obovata 801 on metabolism of thromboxane B2 and arachidonic acid and on platelet aggregation in patients with coronary heart disease and cerebral thrombosis]. Ito, M., Nakashima, H., Baba, M., Pauwels, R., De Clercq, E., Shigeta, S., and Yamamoto, N. Inhibitory effect of glycyrrhizin on the in vitro infectivity and cytopathic activity of the human immunodeficiency virus [HIV (HTLV- III/LAV)]. J Nutr 2001;131:1471-8. People who regularly take large amounts of licorice, more than 20 g/day, may raise blood levels of the hormone aldosterone, which can cause serious side effects, including headache, high blood pressure, and heart problems. View abstract. View abstract. Biol Pharm Bull. We currently have no information for PEONY overview. Lozenge-induced hypermineralcorticoid state--a unique case of licorice lozenges resulting in hypertension and hypokalemia. View abstract. J Altern Complement Med. Early evidence suggests that taking 45 grams of a specific product containing peony and licorice (Peony-Glycyrrhiza Decoction, PGD) daily for 4 weeks reduces levels of a hormone called prolactin in women with high levels of prolactin, without affecting other hormone levels or mental symptoms. Kang, D. G., Moon, M. K., Choi, D. H., Lee, J. K., Kwon, T. O., and Lee, H. S. Vasodilatory and anti-inflammatory effects of the 1,2,3,4,6-penta-O-galloyl-beta-D-glucose (PGG) via a nitric oxide-cGMP pathway. Phytother Res. Teelucksingh S, Mackie AD, Burt D, McIntyre MA, Brett L, Edwards CR. Deglycyrrhizinated liquorice in aphthous ulcers. Man SC, Li XB, Wang HH, et al. Tamir S, Eizenberg M, Somjen D, et al. Korri, H., Awada, A., Baajour, W., Beaini, M., and Nasreddine, W. [Rapidly progressing quadriparesis secondary to licorice (souss) intoxication]. Chin, Y. W., Jung, H. A., Liu, Y., Su, B. N., Castoro, J. Neth J Med 2005;63:146-8. Dellow EL, Unwin RJ, Honour JW. Zhong Xi Yi Jie He Za Zhi 1986;6:714-6, 707. View abstract. Some of these health benefits have also . Exp Clin Endocrinol Diabetes 2003;111:341-3. Phytother Res 2006;20(8):687-695. [Severe hypokalemia after holidays return]. Gao, X., Wang, W., Wei, S., and Li, W. [Review of pharmacological effects of Glycyrrhiza radix and its bioactive compounds]. Kumada T, et al. View abstract. Zhongguo Zhong.Yao Za Zhi 2009;34(21):2695-2700. Electronic Code of Federal Regulations. Cancer Lett. Zhongguo Zhong Xi Yi Jie He Za Zhi 2008;28(4):314-317. Madisch A, Melderis H, Mayr G, et al. Kitagawa, I., Chen, W. Z., Hori, K., Harada, E., Yasuda, N., Yoshikawa, M., and Ren, J. Z., Zhang, Y. Liang, R. N., Liu, J., and Lu, J. 2010 Nov;35(10):1587-93. The inhibition of phenylhydroquinone-induced oxidative DNA cleavage by constituents of Moutan Cortex and Paeoniae Radix. Licorice might decrease the effects of warfarin. View abstract. Fang, J. Y. Helpful. View abstract. Br Med J 1971;3(773):501-503. Am J Chin Med 1996;24:165-8. Not too many side effects of peony tea that we need to worry about. J Med Liban 2012;60(2):117-119. Li G, Simmler C, Chen L, et al. Liang, R., Chen, M. R., and Xu, X. Can J Cardiol 2009;25(10):e357-e358. Ann Noninvasive Electrocardiol. View abstract. J Clin Anesth 2019;54:25-32. Prieto JM, Recio MC, Giner RM, et al. J Agric Food Chem 6-13-2007;55(12):4691-4697. View abstract. View abstract. Kraus SD, Kaminskis A. A randomized, double-blind comparison of licorice versus sugar-water gargle for prevention of postoperative sore throat and postextubation coughing. View abstract. Prospective study]. Br Med J 9-17-1977;2(6089):738-739. Peony and its major constituent, paeoniflorin, improve radial maze performance impaired by scopolamine in rats. View abstract. Taking licorice and loop diuretics together might make potassium levels drop too low. Endocrinol Jpn 1991;38(2):167-174. Lancet 2-10-1979;1(8111):319. Wen Y, Tang Y, Li M, Lai Y. Severe hypokalemic paralysis and rhabdomyolysis due to ingestion of liquorice. View abstract. Guo, D., Ye, G., and Guo, H. A new phenolic glycoside from Paeonia lactiflora. Licorice is available in many different types of products, including candies, lozenges, teas, chewing, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, Getting Help for a Loved One With Psychosis: It's Complicated, Health News and Information, Delivered to Your Inbox, Side effects in people after breathing tube removal. J Assoc Physicians India 1978;26(9):811-814. Takahara T, Watanabe A, Shiraki K. Effects of glycyrrhizin on hepatitis B surface antigen: a biochemical and morphological study. Astragalus may interact with medications that suppress the . Zhonghua Yi Xue Za Zhi 1983;63:477-81. [RETRACTED]. I like herbal and fuit teas and a particular favourite of mine contains liquorice. View abstract. Astragalus may be safe when used orally and appropriately. Apparantly it's the one most important thing that shouldn't mix with Prednisolone and it makes withdrawal symptoms much worse. J Steroid Biochem Mol Biol 1994;49:81-5. View abstract. Pharmacol Biochem Behav 1993;45:719-23. . View abstract. The licorice root derived isoflavan glabridin inhibits the activities of human cytochrome P450S 3A4, 2B6, and 2C9. Nasal irrigation with Glycyrrhiza glabra extract for treatment of allergic rhinitis - A study of in vitro, in vivo and clinical trial. Peony and Licorice is a safe and gentle yet powerful formula that is famous for its ability to build blood and balance menstrual cycles. Chien, C. F., Wu, Y. T., and Tsai, T. H. Biological analysis of herbal medicines used for the treatment of liver diseases. J Pharm Pharmacol 2003;55:1275-82. View abstract. A controlled trial of a dissolving oral patch concerning glycyrrhiza (licorice) herbal extract for the treatment of aphthous ulcers. 2019;18(Suppl1):291-301. Brush, J., Mendenhall, E., Guggenheim, A., Chan, T., Connelly, E., Soumyanath, A., Buresh, R., Barrett, R., and Zwickey, H. The effect of Echinacea purpurea, Astragalus membranaceus and Glycyrrhiza glabra on CD69 expression and immune cell activation in humans. A dual investigation of the effect of dietary supplementation with licorice flavonoid oil on anthropometric and biochemical markers or health and adiposity. A controlled trial of traditional Chinese herbal medicine in Chinese patients with recalcitrant atopic dermatitis. J Endocrinol Invest 1990;13(10):847-848. Kim YR, Nam SH. I. Elucidation of five new flavonoid constituents from the roots of Glycyrrhiza glabra L. collected in Xinjiang. Z Gastroenterol 2001;39(7):511-7. Sun, W. S., Imai, A., Tagami, K., Sugiyama, M., Furui, T., and Tamaya, T. In vitro stimulation of granulosa cells by a combination of different active ingredients of unkei-to. View abstract. Zhong.Xi.Yi.Jie.He.Za Zhi. In 1977, researchers reported the case of a 58-year-old woman who was eating a whopping 1.8 kilograms (about 63.5 ounces) of black licorice per week and went into cardiac arrest. Licorice reduces body fat mass in obese men and women. Evid Based Complement Alternat Med. 1998;111(7):585-587. View abstract. Yoon JY, Cha JM, Hong SS, et al. Rackova, L., Jancinova, V., Petrikova, M., Drabikova, K., Nosal, R., Stefek, M., Kostalova, D., Pronayova, N., and Kovacova, M. Mechanism of anti-inflammatory action of liquorice extract and glycyrrhizin. J Clin Psychopharmacol 2016;36(6):572-9. This formula has also been shown to dramatically relieve various types of spasmodic pain such as muscle cramps in the back and legs (restless legs) stiff muscles premenstrual cramping sciatica and abdominal pain. Rees, W. D., Rhodes, J., Wright, J. E., Stamford, L. F., and Bennett, A. J Clin Psychopharmacol 1997;17(3):234-235. Isaia, G. C., Pellissetto, C., Ravazzoli, M., and Tamone, C. Acute adrenal crisis and hypercalcemia in a patient assuming high liquorice doses. Clin Ther 1999;21(12):2080-2090. Growth-inhibiting, bactericidal, and urease inhibitory effects of Paeonia lactiflora root constituents and related compounds on antibiotic-susceptible and -resistant strains of Helicobacter pylori. View abstract. Intern Med 2007;46:575-8. A preliminary open trial on interferon stimulator (SNMC) derived from Glycyrrhiza glabra in the treatment of subacute hepatic failure. Ir J Med Sci 2016;185(4):945-7. Lapi F, Gallo E, Bernasconi S, et al. View abstract. Reuter, J., Merfort, I., and Schempp, C. M. Botanicals in dermatology: an evidence-based review. Chem Pharm Bull (Tokyo) 1994;42(5):1056-1062. Heavy consumption of licorice during pregnancy has been associated with premature birth and health problems in the child. It's not suggested to take St. John's wort if you take blood thinners. View abstract. Am J Chin Med 2001;29(3-4):459-467. World J Gastroenterol 2005;11:2124-9. . But I didn't take it long enough to see any change. View abstract. View abstract. Paeoniflorin, a constituent of white peony root, has demonstrated inhibition of testosterone synthesis in vitro, without affecting estradiol synthesis.It reduces testosterone production by the ovaries but not the adrenal glands. Eagon PK, Elm MS, Hunter DS, et al. Koo YK, Kim JM, Koo JY, et al. View abstract. Objective: To evaluate the effect of different ratio of peony and licorice and Christina Loosestrife herb decoction on isolated in New Zealand . Clin Pharmacol Ther 1996;59:62-71. Cancer Res 2000;60:5704-9.. View abstract. Licorice might change how quickly the liver breaks down these medications. Removes excess melanin: Licorice extract brightens the skin in another way, too. Adjuvant role of a new emollient cream in patients with palmar and/or plantar psoriasis: a pilot randomized open-label study. Int J Cardiol 2008;124(3):e42-e44. Muscle cramps.Early research suggests that taking a specific combination of peony and licorice (Shakuyaku-kanzoh-to) might ease muscle cramps in people with liver cirrhosis and in people undergoing hemodialysis. Licorice, tobacco chewing, and hypertension. [Effect of dandi tablet on blood lipids and sex hormones in women of postmenopausal stage]. therapy. This could change the effects and side effects of these medications. View abstract. Liquorice-induced rise in blood pressure: a linear dose-response relationship. $9.44 $ 9. Microbiol Immunol 2000;44(9):799-804. We describe a patient who suffered life-threatening hypokalemic paralysis caused by consumption of licorice in the form of a tea sweetener superimposed on long . [Clinical characteristics of five elderly patients with severe hypokalemia induced by glycyrrhizin derivatives]. View abstract. 6 Top Celery Juice Benefits & Side Effects. Berlango Jimenez A., Jimenez Murillo L., Montero Perez F. J., Munoz Avila J. View abstract. Dong quai grows at high altitudes in the cold, damp, mountains of China, Korea, and Japan. View abstract. Most clinical trials have found that when Peony is combined with Licorice Rt. Dobbins, K. R. and Saul, R. F. Transient visual loss after licorice ingestion. This can increase the effects and side effects of corticosteroids. View abstract. Licorice is believed to have anti-androgenic effects, meaning that it may be active to reduce testosterone levels. (Tokyo) 2008;54(3):244-249. Life Sci 2-23-2001;68(14):1687-1694. J Nutr Sci Vitaminol. J Infect.Chemother. J Hum Hypertens 2001;15:549-52. Nahidi F, Zare E, Mojab F, Alavi-Majd H. Effects of licorice on relief and recurrence of menopausal hot flashes. Neth J Med 2005;63:149-50. 1991;78(1-2):1-6. J Ethnopharmacol. BMJ 1997;314:731-2. Licorice is an herb that grows in parts of Europe and Asia. View abstract. Muscle cramps.Early research suggests that taking a specific combination of peony and licorice (Shakuyaku-kanzoh-to) might ease muscle cramps in people with liver cirrhosis and in people undergoing hemodialysis. The benefits of licorice root can be enjoyed as a tea, supplement, tincture, or topical treatment, and even as candies. View abstract. Life Sci 2005;78:413-20 . View abstract. Therapeutic basis of glycyrrhizin on chronic hepatitis B. Antiviral Res 1996;30:171-7. View abstract. View abstract. View abstract. View abstract. Feng ZT, Xu J, He GC, Cai SJ, Li J, Mei ZG. View abstract. Cochrane Database Syst Rev 2004;4:CD002291. Influence of traditional Chinese anti-inflammatory medicinal plants on leukocyte and platelet functions. QJM 2011;104(12):1093-1095. About Dr.Cope. Erratum in: Clin Rheumatol. Biol Pharm Bull. Zheng, A. and Moritani, T. Effect of the combination of ginseng, oriental bezoar and glycyrrhiza on autonomic nervous activity and immune system under mental arithmetic stress. Medicine (Baltimore) 2018;97(11):e0073. Bian, X., Xu, Y., Zhu, L., Gao, P., Liu, X., Liu, S., Qian, M., Gai, M., Yang, J., and Wu, Y. Z. 17. Clin Exp Obstet Gynecol 2013;40(1):141-143. View abstract. 10. Era of Hope Mtg, Dept Defense; Breast Cancer Res Prog, Atlanta, GA 2000;Jun 8-11. Cancer 1997;79(8):1494-1500. The chemicals in licorice are thought to . View abstract. Hsiu, S. L., Lin, Y. T., Wen, K. C., Hou, Y. C., and Chao, P. D. A deglucosylated metabolite of paeoniflorin of the root of Paeonia lactiflora and its pharmacokinetics in rats. PC-SPES, a dietary supplement for the treatment of hormone-refractory prostate cancer. Mol Nutr Food Res 2006;50(11):1080-1086. View abstract. View abstract. Cumming, A. M., Boddy, K., Brown, J. J., Fraser, R., Lever, A. F., Padfield, P. L., and Robertson, J. I. View abstract. Therapeutic Research Faculty 2020. Zhang W, Dai SM. An evaluation of the efficacy of licorice gargle for attenuating postoperative sore throat: a prospective, randomized, single-blind study. Some birth control pills contain estrogen. Cureus 2020;12(11):e11656. Effect of orally administered shao-yao-gan-cao-tang (Shakuyaku-kanzo-to) on muscle cramps in maintenance hemodialysis patients: a preliminary study. Janse A, van Iersel M, Hoefnagels WH, Olde Rikker MG. Hasegawa, J., Suyama, Y., Kinugawa, T., Morisawa, T., and Kishimoto, Y. Echocardiographic findings of the heart resembling dilated cardiomyopathy during hypokalemic myopathy due to licorice-induced pseudoaldosteronism. Nippon Rinsho 1994;52:1817-22. Phytother.Res 2004;18(3):241-243. It is used for stomach pain, abdominal pain and acute pain of gastrocnemius muscle contracture, etc. Cisplatin is used to treat cancer. View abstract. Immunopharmacology 1999;41(3):169-181. Meta-analysis: phytotherapy of functional dyspepsia with the herbal drug preparation STW 5 (Iberogast). 2018 Jan;37(1):35-42. doi: 10.1007/s10067-017-3770-y. Attou R, Redant S, Honore PM, Preseau T, Hantson P, De Bels D. Liquorice intoxication can lead to cardiac arrest! View abstract. View abstract. Zhong Yao Cai 2000;23:557-60. . Chen MF, Shimada F, Kato H, Yano S, Kanaoka M. Effect of glycyrrhizin on the pharmacokinetics of prednisolone following low dosage of prednisolone hemisuccinate. Fuhrman, B., Volkova, N., Kaplan, M., Presser, D., Attias, J., Hayek, T., and Aviram, M. Antiatherosclerotic effects of licorice extract supplementation on hypercholesterolemic patients: increased resistance of LDL to atherogenic modifications, reduced plasma lipid levels, and decreased systolic blood pressure. Ruiz-Granados, E. S., Shouls, G., Sainsbury, C., and Antonios, T. A salty cause of severe hypertension. Cotterill, J. Isr J Dent Sci 1989;2(3):153-157. Neurology 2010;75(21):1939-1941. Lee, S. J., Lee, H. M., Ji, S. T., Lee, S. R., Mar, W., and Gho, Y. S. 1,2,3,4,6-Penta-O-galloyl-beta-D-glucose blocks endothelial cell growth and tube formation through inhibition of VEGF binding to VEGF receptor. Contact Dermatitis 2021;85(4):454-455. View abstract. Russo S, Mastropasqua M, Mosetti MA, et al. Am J Psychiatry 1994;151:617-8. Gatica-Ortega ME, Pastor-Nieto MA. View abstract. View abstract. Severe hypokalaemia with paralysis induced by small doses of liquorice. Pontefract cakes can be bad for you: refractory hypertension and liquorice excess. White peony root is very much essential and used in Chinese medicine because of its medicinal properties. Hsu, Y. L., Wu, L. Y., Hou, M. F., Tsai, E. M., Lee, J. N., Liang, H. L., Jong, Y. J., Hung, C. H., and Kuo, P. L. Glabridin, an isoflavan from licorice root, inhibits migration, invasion and angiogenesis of MDA-MB-231 human breast adenocarcinoma cells by inhibiting focal adhesion kinase/Rho signaling pathway. Harada M, Suzuki M, Ozaki Y. Arase, Y., Ikeda, K., Murashima, N., Chayama, K., Tsubota, A., Koida, I., Suzuki, Y., Saitoh, S., Kobayashi, M., and Kumada, H. The long term efficacy of glycyrrhizin in chronic hepatitis C patients. View abstract. Lin SH, Yang SS, Chau T, Halperin ML. Licorice can be used orally with Peony to treat women with Polycystic Ovary Syndrom to increase fertility; it can also treat patients with abnormal Prolactin, muscle spasms, or to reduce the pain of cancer. 2016 Nov;48(11):1873-1880. doi: 10.1007/s11255-016-1345-5. View abstract. Report of a new case]. Deng, Y. Y., Chen, Y. P., Wang, L., Hu, Z., Jin, Y., Shen, L., Zhu, R., and Zhong, Y. Antiviral Res 1987;7(3):127-137. 2013 Nov;18(6):593-6. Sontia B, Mooney J, Gaudet L, Touyz RM. Complement Ther Med. May Harm Baby During Pregnancy. Preterm birth and licorice consumption during pregnancy. Postgrad Med J 1980;56(657):526-529. View abstract. Phytother.Res. Tu, J. H., He, Y. J., Chen, Y., Fan, L., Zhang, W., Tan, Z. R., Huang, Y. F., Guo, D., Hu, D. L., Wang, D., and Hong-Hao Zhou. View abstract. View abstract. Further studies on the mechanism of the mineralocorticoid action of licorice in humans. View abstract. Health Care Women Int. Lin, J. C. Mechanism of action of glycyrrhizic acid in inhibition of Epstein-Barr virus replication in vitro. J Hum Hypertens 2003;17(2):125-131. "Water pills" can also decrease potassium levels. Bardhan, K. D., Cumberland, D. C., Dixon, R. A., and Holdsworth, C. D. Clinical trial of deglycyrrhizinised liquorice in gastric ulcer. Zhu Q, Qi X, Wu Y, Wang K. Clinical study of total glucosides of paeony for the treatment of diabetic kidney disease in patients with diabetes mellitus. View abstract. Fitoterapia 2006;77(7-8):613-614. Klin Wochenschr 1983;61:303-5. View abstract. View abstract. 2005 - 2023 WebMD LLC. The immediate effect of Shakuyaku-kanzo-to, traditional Japanese herbal medicine, for muscular cramps during maintenance hemodialysis. Estrogenic activity of herbs commonly used as remedies for menopausal symptoms. . Bell ZW, Canale RE, Bloomer RJ. J Am Acad Dermatol 2011;65(4):699-714. Wong, A. L. and Chan, T. Y. Interaction between warfarin and the herbal product quilinggao. Kroes, B. H., Beukelman, C. J., van den Berg, A. J., Wolbink, G. J., van Dijk, H., and Labadie, R. P. Inhibition of human complement by beta-glycyrrhetinic acid. View abstract. A., van der Ven, P. F., Martin, M., Sherman, J., and Haley, J. View abstract. Fitoterapia 2004;75:45-9.. View abstract. Sakamoto S, Kudo H, Suzuki S, et al. Eur J Obstet Gynecol.Reprod Biol 2007;131(1):61-67. But not everyone will have the side . Antimicrobial isoflavanoids and related substances from Glycyrrhiza glabra L. var. It's thought liquorice's side-effects are caused by the glycyrrhizic acid, but it is possible to buy deglycyrrhizinated liquorice (DGL), which may help prevent these issues. Digestion 2004;69:45-52. Altern Med Rev 1999;4(3):178-188. J Altern Complement Med 2010;16(10):1065-1071. View abstract. Efficiency and safety of desloratadine in combination with compound glycyrrhizin in the treatment of chronic urticaria: a meta-analysis and systematic review of randomised controlled trials. Foster CA, Church KS, Poddar M, Van Uum SH, Spaic T. Licorice-induced hypertension: a case of pseudohyperaldosteronism due to jelly bean ingestion. View abstract. J Clin Psychopharmacol 1997;17(3):234-235. Chamberlain, J. J. and Abolnik, I. Yamada, K., Kanba, S., Yagi, G., and Asai, M. Effectiveness of herbal medicine (shakuyaku-kanzo-to) for neuroleptic-induced hyperprolactinemia. Anesth Analg. It might also decrease the effects of birth control pills. When eaten in large quantities, black licorice can cause serious health issues. Xie HJ, Yasar U, Sandberg M, Rane A. Paeoniae Radix, a traditional Chinese medicine, and CYP2C9 activity. MacKenzie, M. A., Hoefnagels, W. H., Jansen, R. W., Benraad, T. J., and Kloppenborg, P. W. The influence of glycyrrhetinic acid on plasma cortisol and cortisone in healthy young volunteers. 2017;109:182-190. Sigurjonsdottir HA, Ragnarsson J, Franzson L, Sigurdsson G. Is blood pressure commonly raised by moderate consumption of liquorice? Menopause 2002;9:145-50. J Clin Endocrinol Metab 1990;70(6):1637-1643. View abstract. J Altern Complement Med 2000;6:557-9. View abstract. The U.S. Food and Drug . View abstract. View abstract. Hawrelak, J. Effect of glycyrrhizin-containing toothpaste on dental plaque reduction and gingival health in humans. View abstract. J Tradit.Chin Med 2010;30(1):47-50. Blood Press 2009;18:192-5. Anesth Analg 2009;109(1):77-81. Crit Care 2011;15(1):R64. [Clinical observation on auxiliary treatment of hormone dependence dermatitis by shufeng liangxue decoction]. [Clinical study on treatment of mid-advanced crescentic nephritis by qingre huoxue recipe]. View abstract. Brasseur, A. and Ducobu, J. Journal of Clinical Therapeutics Medicine. Nephron 2002;90:240. View abstract. It has an effect similar to aldosterone. Eriksson JW, Carlberg B, Hillom V. Life-threatening ventricular tachycardia due to liquorice-induced hypokalemia. View abstract. Information from this source is evidence-based and objective, and without commercial influence. View abstract. Oh, G. S., Pae, H. O., Choi, B. M., Jeong, S., Oh, H., Oh, C. S., Rho, Y. D., Kim, D. H., Shin, M. K., and Chung, H. T. Inhibitory effects of the root cortex of Paeonia suffruticosa on interleukin-8 and macrophage chemoattractant protein-1 secretions in U937 cells. Phytother Res 2008;22:563-5. View abstract. Antiviral Res 1987;7(2):99-107. However, taking too much licorice root may cause side effects. The anti-estrogenic action of beta-glycyrrhetinic acid. View abstract. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Lee, S. J., Lee, I. S., and Mar, W. Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 activity by 1,2,3,4,6-penta-O-galloyl-beta-D-glucose in murine macrophage cells. J Hypertens 1985;3(1):19-23. CJEM 2010;12(3):224-225. [Protective mechanism of Salvia miltiorrhiza and Paeonia lactiflora for experimental liver damage]. View abstract. Qi XG. View abstract. Hukkanen J, Ukkola O, Savolainen MJ. View abstract. *. View abstract. View abstract. View abstract. [Clinical observations on the treatment of the gestational hypertension syndrome with Angelica and Paeonia powder]. View abstract. Sheehan MP, Atherton DJ. Am J Chin Med 2005;33(5):747-758. 2016 Oct;39:314-319. doi: 10.1016/j.intimp.2016.08.006. View abstract.